Vaccine
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How often
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Disease prevented
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Who needs it
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Recombinant zoster vaccine (RZV)
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2 doses, the second dose given 2 to 6 months after the first
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Herpes zoster (shingles), a painful rash marked by blisters
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Adults ages 50 and older. This is given even if you've had shingles before or had a previous zoster live vaccine (ZVL). The live vaccine is no longer available in the U.S.
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Some adults ages 19 and older with a weak immune system may be advised to get RZV. Talk with your health care provider about your situation.
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Respiratory syncytial virus (RSV)
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1 dose for older adults. Seasonal administration during pregnancy.
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RSV is a common respiratory virus that usually causes mild, cold-like symptoms. Most people recover in a week or two, but RSV can be serious in older adults, infants, and people with certain conditions.
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All adults ages 75 and older. Adults ages 60-74 at increased risk of severe RSV.
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To prevent severe RSV disease in infants, CDC recommends either maternal RSV vaccination at 32 through 36 weeks of pregnancy September through January, or infant RSV immunization with monoclonal antibody. Most infants will not need both.
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Measles, mumps, rubella (MMR)**
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1 or 2 doses, for ages 19 through 49. 1 dose for ages 50 and older if at risk. An extra dose may be advised in areas of mumps outbreaks.
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Measles, a disease marked by red spots, fever, and coughing
Mumps, a disease that causes swelling in the salivary glands. It may affect the ovaries or testes.
Rubella (German measles). This is a form of measles that can cause birth defects if a pregnant woman gets it.
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Adults born in 1957 and later who are not known to be immune to measles, mumps, or rubella. Ask your health care provider if you need a second dose.
**This vaccine should not be given to pregnant women. Women should prevent pregnancy for 4 weeks after vaccination.
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Meningococcal
Two types of vaccines are available depending on age and medical situation:
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1 or more doses depending on vaccine type and condition
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Meningococcal disease (bacterial meningitis). This is inflammation of the membrane covering the brain and spinal cord. It can lead to death.
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Adults with immune deficiencies or at high risk of exposure. Also, first-year college students living in residential housing (if not vaccinated at age 16 or older). Also, military recruits.
Ask your health care provider about meningococcal disease and which vaccine may be right for you.
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Hepatitis A (HepA)
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One series of 2 to 3 injections depending on the vaccine
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Hepatitis A. This is an infection that can result in acute liver inflammation and yellow skin and whites of the eyes (jaundice).
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Adults with risk factors, such as clotting disorders or chronic liver disease, and adults with high risk of exposure. This includes men who have sex with men, injection drug users, and travelers to countries where hepatitis A is common.
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Hepatitis B (HepB)
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One series of 2, 3, or 4 doses depending on the vaccine, age, risk, or condition
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Hepatitis B. This is an infection that causes chronic, severe liver disease.
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Adults with high risk of exposure, such as health care providers, sanitation workers, and adults with diabetes. This includes people living with HIV if not already immune.
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Travelers’ diseases
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As needed
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Infections, such as cholera, typhoid, yellow fever, polio, rabies, meningococcal disease, hepatitis A, hepatitis B
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Adults traveling out of the country. Required vaccines will vary, depending on the country you visit. Check the CDC website at www.cdc.gov/travel .
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